tozasertib

a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth

Also Known As:

MK-0457; MK0457; N- (4- ((4- (4- methylpiperazin- 1- yl)- 6- ((5- methyl- 1H- pyrazol- 3- yl)amino)pyrimidin- 2- yl)sulfanyl)phenyl)cyclopropanecarboxamide; N- (4- ((4- (4- methylpiperazin- 1- yl)- 6- ((5- methyl- 1H- pyrazol- 3- yl)amino)pyrimidin- 2- yl)sulfanyl)phenyl)cyclopropanecarboxamide lactate; N- (4- ((4- (4- methylpiperazin- 1- yl)- 6- ((5- methyl- 1H- pyrazol- 3- yl)amino)pyrimidin- 2- yl)sulfanyl)phenyl)cyclopropanecarboxamide, (2S)-2-hydroxypropanoate; VE 465; VE-465; VX-680; VX-680 lactate; VX680; VX680 lactate; cyclopropane carboxylic acid N- (4- (4- (4- methylpiperazin- 1- yl)- 6- (5- methyl- 2H- pyrazol- 3- ylamino)pyrimidin- 2- ylsulfanyl)phenyl)amide; tozasertib lactate

Organic Chemicals: 140
- Hydrocarbons: 1726
  - Cyclic Hydrocarbons: 96
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclopropanes: 9
        tozasertib: 90
Heterocyclic Compounds: 207
- 1-Ring Heterocyclic Compounds
  - Azoles: 2199
    - Pyrazoles: 61
      - tozasertib: 90
  - Pyrimidines: 521
    - tozasertib: 90
  - Piperazines: 26
    - tozasertib: 90

S J Freedman Selected Research

S J Freedman Research Topics

Disease

Drug/Important Bio-Agent (IBA)